The Bioinformatic Analysis of the Dysregulated Genes and MicroRNAs in Entorhinal Cortex, Hippocampus, and Blood for Alzheimer's Disease.

Xiaocong PangYing ZhaoJinhua WangQimeng ZhouLvjie XuDe KangAi-Lin Liu Guan-Hua Du

Published in: BioMed research international (2017)

These biological pathways and DEGs or hub genes will be useful to elucidate AD pathogenesis and identify novel biomarkers or drug targets for developing improved diagnostics and therapeutics against AD.

Keyphrases

bioinformatics analysis
genome wide
genome wide identification
small molecule
cognitive decline
genome wide analysis
dna methylation
gene expression
transcription factor
cerebral ischemia
prefrontal cortex
blood brain barrier
mild cognitive impairment