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Successful treatment with placenta-derived decidual stromal cells in a pediatric patient with life-threatening acute gastrointestinal graft-versus-host disease.

Britt GustafssonPer FriskAttilla SzakosBehnam SadeghiOlle RingdénBritt-Marie Frost
Published in: Pediatric transplantation (2017)
Severe aGvHD is a life-threatening complication after allogeneic HSCT. The GI tract is considered to play a key role in aGvHD, where the disease process can start and is one of the major target organs. Here, we present a case of a one-year-old child with a life-threatening GI-aGvHD stage IV, post-HSCT, resistant to steroids and MMF for 4 weeks. He was successfully treated with placenta-derived DSC.
Keyphrases
  • hematopoietic stem cell
  • liver failure
  • stem cell transplantation
  • drug induced
  • mental health
  • bone marrow
  • early onset
  • respiratory failure
  • low dose
  • aortic dissection
  • high dose
  • gestational age
  • natural killer cells