Pseudomonas aeruginosa necrotizing bronchopneumonia.
Ranjit I KylatPublished in: Autopsy & case reports (2021)
Extremely low birth weight (ELBW) infants are at particularly high risk for infection due to an immature immune system, invasive procedures such as endotracheal intubation, intravascular catheterization, and other factors. Neonatal infections in this population are associated with a high mortality, poor growth, and neurodevelopmental outcomes. Pseudomonas aeruginosa (P. aeruginosa) infection is an uncommon but potentially devastating cause of pneumonia and sepsis in the ELBW population. P. aeruginosa is an important cause of healthcare-associated infections (HAI) or nosocomial infections. P. aeruginosa can perceive unfavorable environmental changes and orchestrate adaptations by developing plasmid-mediated and adaptive resistance to antibiotics. We describe an ELBW infant born at 26 weeks' gestation who succumbed at 13 days of life to P. aeruginosa infection. Some of the factors related to the pathogenesis and multidrug resistance are described.
Keyphrases
- low birth weight
- pseudomonas aeruginosa
- preterm infants
- healthcare
- cystic fibrosis
- preterm birth
- human milk
- gestational age
- acinetobacter baumannii
- escherichia coli
- cardiac arrest
- intensive care unit
- coronary artery
- cardiovascular events
- crispr cas
- acute kidney injury
- coronary artery disease
- risk factors
- drug resistant
- skeletal muscle
- high intensity
- weight loss
- extracorporeal membrane oxygenation
- health insurance
- acute respiratory distress syndrome
- health information
- community acquired pneumonia
- respiratory failure
- affordable care act