Genetic Variants within NOGGIN, COL1A1, COL5A1, and IGF2 are Associated with Musculoskeletal Injuries in Elite Male Australian Football League Players: A Preliminary Study.

Ysabel JacobRyan S AndertonJodie L Cochrane WilkieBrent RogalskiSimon M LawsAnthony JonesTania SpiteriDana HinceNicolas H Hart

Published in: Sports medicine - open (2022)

Our preliminary study is the first to examine associations between genetic variants and injury in Australian Football. NOGGIN rs1372857-GG, COL5A1 rs12722-TT, IGF2 rs3213221-CC, and COL1A1 rs1800012-TT genotypes held various associations with muscle-, bone-, tendon- and ligament-related injuries of differing severities. To further increase our understanding of these, and other, genetic variant associations with injury, competition-wide AFL studies that use more players and a larger array of gene candidates is essential.

Keyphrases

high school
genome wide
copy number
skeletal muscle
pi k akt
body composition
high resolution
gene expression
dna methylation
cell proliferation
transcription factor
single cell
high density
anterior cruciate ligament reconstruction
genome wide identification