The impact of fracture liaison services on subsequent fractures and mortality: a systematic literature review and meta-analysis.
Nannan LiM HiligsmannA BoonenM M van OostwaardR T A L de BotC E WyersS P G BoursJ P van den BerghPublished in: Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA (2021)
This systematic review and meta-analysis suggests that FLS care is associated with a significantly lower probability of subsequent fractures and mortality although the latter was only found in studies comparing outcomes before and after the introduction of an FLS. The quality assessment revealed that some important methodological issues were unmet in the currently available studies. Recommendations to guide researchers to design high-quality studies for evaluation of FLS outcomes in the future were provided.