Role of the putative PKC phosphorylation sites of the type IIc sodium-dependent phosphate transporter in parathyroid hormone regulation.

Toru FujiiHiroko SegawaAi HanazakiShiori NishiguchiSakura MinoshimaAkiko OhiRieko TominagaSumire SasakiKazuya TanifujiMegumi KoikeYuki ArimaYuji ShiozakiIchiro KanekoMikiko ItoSawako TatsumiKen-Ichi Miyamoto

Published in: Clinical and experimental nephrology (2019)

The present study suggests that acute regulation of NaPi-IIc protein by PTH is involved in the inactivation of Na+-dependent Pi cotransporter activity and that phosphorylation of the transporter is involved in the rapid modification.

Keyphrases

protein kinase
liver failure
respiratory failure
drug induced
amino acid
small molecule
aortic dissection