2-Deoxy-2-[18 F]fluoro-d-glucose positron emission tomography, cortical thickness and white matter graph network abnormalities in brains of patients with amyotrophic lateral sclerosis and frontotemporal dementia suggest early neuronopathy rather than axonopathy.

Published in: European journal of neurology (2020)

Abnormalities in significantly fewer WM networks underlying the affected cortical regions suggest that neurodegeneration in brains of ALS-FTD patients is primarily a 'neuronopathy' rather than an 'axonopathy.'

Keyphrases

positron emission tomography
amyotrophic lateral sclerosis
computed tomography
white matter
end stage renal disease
ejection fraction
newly diagnosed
chronic kidney disease
pet ct
prognostic factors
pet imaging
optical coherence tomography
patient reported outcomes
blood glucose
insulin resistance