Incidences and Risk Factors of Organ Manifestations in the Early Course of Systemic Sclerosis: A Longitudinal EUSTAR Study.

Veronika K JaegerElina G WirzYannick AllanorePhilipp RossbachGabriela RiemekastenEric HachullaOliver DistlerPaolo AiròPatricia E CarreiraAlexandra Balbir GurmanMohammed TiklySerena VettoriNemanja DamjanovUlf Müller-LadnerJörg H W DistlerMangtao LiUlrich A Walkernull null

Published in: PloS one (2016)

In SSc patients presenting early after RP onset, approximately half of all incident organ manifestations occur within 2 years and have a simultaneous rather than a sequential onset. These findings have implications for the design of new diagnostic and therapeutic strategies aimed to 'widen' the still very narrow 'window of opportunity'. They may also enable physicians to counsel and manage patients presenting early in the course of SSc more accurately.

Keyphrases

systemic sclerosis
end stage renal disease
risk factors
chronic kidney disease
cardiovascular disease
prognostic factors
interstitial lung disease
peritoneal dialysis
rheumatoid arthritis
case report