Prospective evaluation of two specific IgG immunoassays (HemosIL® AcuStar HIT-IgG and HAT45G® ) for the diagnosis of heparin-induced thrombocytopenia: A Bayesian approach.

AcuStar HIT® detects more than 90% of HIT, as do all rapid IAs, and appears to be a good tool for excluding HIT when the pretest probability is intermediate. A chemiluminescent signal higher than 10 IU/mL is highly predictive of definite HIT with a PPV of 100%.