Integrative Genomic Profiling Uncovers Therapeutic Targets of Acral Melanoma in Asian Populations.

Qiong ShiLin LiuJianru ChenWeigang ZhangWeinan GuoXiao WangHuina WangSen GuoQiao YueJingjing MaYu LiuGuannan ZhuTao ZhaoJianhong ZhaoYing LiuTianwen GaoChunying Li

Published in: Clinical cancer research : an official journal of the American Association for Cancer Research (2022)

Our study provided a detailed view of genomic instability, potential therapeutic targets, and intratumoral heterogeneity of acral melanoma, which might fuel the development of personalized strategies for treating acral melanoma in Asian populations.

Keyphrases

skin cancer
single cell
copy number
basal cell carcinoma
genetic diversity
network analysis