Complete or partial loss of the Y chromosome in an unselected cohort of 865 non-vasectomized, azoospermic men.

Jens Fedder Christina R Fagerberg M W Jørgensen Claus Højbjerg Gravholt Agnethe Berglund Ulla Breth Knudsen Anne Skakkebaek

Published in: Basic and clinical andrology (2023)

In men with azoospermia, Y chromosome loss ranging from small microdeletions to complete loss of the Y chromosome was found in 6.1% (53/865). Partial AZFb microdeletions may give a milder testicular phenotype compared to complete AZFb microdeletions.

Keyphrases

copy number
middle aged