RNF149 Destabilizes IFNGR1 in Macrophages to Favor Postinfarction Cardiac Repair.
Chun-Kai HuangZhiyong ChenZhongxing ZhouShuaijie ChenLongqing ChenLiliang LiTao LiXiaoxiang YanDajun ChaiPublished in: Circulation research (2024)
These findings highlight the significance of RNF149 as a molecular brake on macrophage response to MI and uncover a macrophage-intrinsic posttranslational mechanism essential for maintaining immune homeostasis and facilitating cardiac repair following MI.