Psychological outcomes related to exome and genome sequencing result disclosure: a meta-analysis of seven Clinical Sequencing Exploratory Research (CSER) Consortium studies.
Jill O RobinsonJulia WynnBarbara BieseckerLeslie G BieseckerBarbara BernhardtKyle Bertram BrothersWendy K ChungKurt D ChristensenRobert C GreenAmy L McGuireM Ragan HartIda GriesemerDonald L PatrickChristine RiniDavid VeenstraAngel M CroninStacy W GrayPublished in: Genetics in medicine : official journal of the American College of Medical Genetics (2019)
Our findings across multiple clinical settings suggest no clinically significant psychological harms from the return of ES/GS results. Some populations may experience low levels of test-related distress or greater positive psychological effects. Future research should further investigate the reasons for test-related psychological response variation.