HIV-1 residual risk and pre-treatment drug resistance among blood donors: A sentinel surveillance from Gabon.
Christian MangalaDésiré TakouDenis Maulot-BangolaGrace BeloumouOlivier Rebienot PellegrinSamuel Martin SossoCollins Ambe ChenwiEzechiel Ngoufack Jagni SemengueFranck Vigan CodjoOlga BoussougouAlex Durand NkaMichel TommoNadine FainguemRachel KamgaingVicky Jocelyne Moor AmaHortense Kamga GonsuVeronique PenlapThérèse NkoaVittorio ColizziCarlo-Federico PernoJoseph FokamAlexis NdjoloPublished in: PloS one (2024)
This sentinel surveillance indicates a high residual risk of HIV-1 transfusion in Gabon, thereby underscoring the need for optimal screening strategy for blood safety. Moreover, HIV-1 transmission goes with high-risk of PDR, suggesting suboptimal efficacy of ART. Nonetheless, the genetic diversity has limited (if any effect) on the residual risk of infection and PDR in blood donors.