Predictive biomarkers of resistance to hypofractionated radiotherapy in high grade glioma.

Julian BiauEmmanuel ChautardLeanne De KoningFrank CourtBruno PereiraPierre VerrelleMarie Dutreix

Published in: Radiation oncology (London, England) (2017)

Several compounds targeting EGFR or CHK1 are already in clinical use and combining them with stereotactic hypofractionated radiotherapy for recurrent high grade gliomas might be of particular interest.

Keyphrases

high grade
radiation therapy
brain metastases
low grade
small cell lung cancer
locally advanced
early stage
radiation induced
epidermal growth factor receptor
tyrosine kinase
cancer therapy
dna damage response
dna damage
oxidative stress