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Nucleolar protein TCOF1 maintains gastric cancer cell proliferation by regulating R-loop associated DNA replication stress.

Xin NieChong ZhaoYuan ZhangWenqi HuangYou-Lian ZhouHaiying LiuYu Qiang NieKeping XieLin Jia
Published in: Journal of gastroenterology and hepatology (2023)
These findings demonstrate a novel role of TCOF1 in maintaining GC cell proliferation by alleviating R-loop associated DNA replication stress.
Keyphrases
  • cell proliferation
  • cell cycle
  • transcription factor
  • stress induced
  • pi k akt
  • protein protein
  • heat stress
  • small molecule
  • high resolution
  • gas chromatography
  • liquid chromatography