N -Aminoacyl-3-amino- nido -carboranes as a Group of Boron-Containing Derivatives of Natural Amino Acids.

A new group of nido -carboranyl derivatives of natural ( S )-amino acids containing from 9 to 18 boron atoms was obtained in good yields as a result of acylation of 3-amino-1,2-dicarba- closo -dodecaborane followed by deboronation. The proposed approach is convenient and based on the use of readily available reagents and is suitable for the synthesis of enantiopure nido -carboranyl derivatives of amino acids with various side chains, including water-soluble boron-containing amino acids (17 examples).