Mechanical Stimulation and Diameter of Fiber Scaffolds Affect the Differentiation of Rabbit Annulus Fibrous Stem Cells.

Pinghui ZhouBangguo WeiJingjing GuanYu ChenYansong ZhuYuchen YeYue MengJianzhong GuanYingji Mao

Published in: Tissue engineering and regenerative medicine (2020)

Overlaying the scaffolds with different CTS-stimulated cells could eventually lead to engineered AF tissues with hierarchical structures that approximated the native AF tissue. Thus, the proposed methodologies could be potentially applied for AF regeneration.

Keyphrases

stem cells
atrial fibrillation
induced apoptosis
tissue engineering
cell cycle arrest
gene expression
aortic valve
endoplasmic reticulum stress
cell therapy
cell proliferation
mass spectrometry