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The genomic impact of historical hybridization with massive mitochondrial DNA introgression.

Fernando A SeixasPierre BoursotJosé Melo-Ferreira
Published in: Genome biology (2018)
General nuclear and mtDNA patterns of introgression can be explained by purely demographic processes. Hybrid incompatibilities and interplay between selection and recombination locally modulate levels of nuclear introgression. Selection promoted introgression of some genes involved in conflicts, either interspecific (parasites) or possibly cytonuclear. In the latter case, nuclear introgression could mitigate the potential negative effects of alien mtDNA on mitochondrial metabolism and male-specific traits.
Keyphrases
  • mitochondrial dna
  • copy number
  • genome wide
  • dna methylation
  • oxidative stress
  • risk assessment
  • human health
  • plasmodium falciparum