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The Senolytic Drug JQ1 Removes Senescent Cells via Ferroptosis.

Seokhyeong GoMikyung KangSung Pil KwonMungyo JungOk Hee JeonByung-Seok Kim
Published in: Tissue engineering and regenerative medicine (2021)
The data indicate that JQ1 can eliminate senescent cells via ferroptosis. This study suggests ferroptosis as a new mechanism of senolytic therapy.
Keyphrases
  • cell death
  • cell cycle arrest
  • induced apoptosis
  • endoplasmic reticulum stress
  • stem cells
  • signaling pathway
  • oxidative stress
  • big data