F. nucleatum targets lncRNA ENO1-IT1 to promote glycolysis and oncogenesis in colorectal cancer.
Jie HongFangfang GuoShi-Yuan LuChaoqin ShenDan MaXinyu ZhangYile XieTingting YanTaChung YuTiantian SunYun QianMing ZhongJinxian ChenYanshen PengCheng WangXiang ZhouJianjun LiuQiang LiuXiong MaYing-Xuan ChenHaoyan ChenJing-Yuan FangPublished in: Gut (2020)
F. nucleatum and glucose metabolism are mechanistically, biologically and clinically connected to CRC. Targeting ENO1 pathway may be meaningful in treating patients with CRC with elevated F. nucleatum.