Minocycline and matrix metalloproteinase inhibition in acute intracerebral hemorrhage: a pilot study.

Jason J ChangM Kim-TenserB A EmanuelG M JonesK ChappleA AlikhaniN SanossianW J MackGeorgios K TsivgoulisA V AlexandrovT Pourmotabbed

Published in: European journal of neurology (2017)

High-dose intravenous minocycline can be safely administered to patients with ICH. Larger randomized clinical trials evaluating the efficacy of minocycline and MMP-9 inhibition in ICH patients are required.

Keyphrases

high dose
end stage renal disease
newly diagnosed
ejection fraction
low dose
liver failure
brain injury
prognostic factors
stem cell transplantation
drug induced
patient reported outcomes
intensive care unit
cell migration