Enterovirus and parechovirus meningoencephalitis in infants: A ten-year prospective observational study in a neonatal intensive care unit.
Carlo PietrasantaAndrea RonchiLaura BassiAgnese De CarliLuca CascheraFrancesco Maria Lo RussoBeatrice Letizia CrippaSilvia PisoniRiccardo CrimiGiacomo ArtieriLaura PellegrinelliRobertino DilenaGiorgio ConteFabio MoscaMonica FumagalliLorenza PugniPublished in: Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology (2024)
In our cohort, neonates infected by HPeV had more severe clinical manifestations, more alterations at brain MRI, and some signs of long-term neurodevelopmental delay. Our data highlight the heterogeneity of manifestations in infants with EV or HPeV meningoencephalitis, and the need for long-term follow-up of those infected by HPeV in the neonatal period.