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Association study of candidate genes with obesity and metabolic traits in antipsychotic-treated patients with first-episode psychosis over a 2-year period.

Patricia GassóJoan Albert ArnaizSergi MasAmalia LafuenteMiquel BioqueManuel J CuestaCovadonga M Díaz-CanejaClemente GarcíaAntonio LoboAna González-PintoMara ParelladaIluminada CorripioEduard VietaJosefina Castro-FornielesAnna ManéNatalia RodríguezDaniel BolocJerónimo Saiz-RuizMiguel Bernardonull null
Published in: Journal of psychopharmacology (Oxford, England) (2020)
Although our results should be interpreted as exploratory, they support previous evidence of the impact of these candidate genes on obesity and metabolic status. Further research is required to gain a better knowledge of the genetic variants that can be considered relevant metabolic risk factors. The ability to identify FEP patients at higher risk for these metabolic disturbances would enable clinicians to better select and control their AP treatment.
Keyphrases
  • risk factors
  • metabolic syndrome
  • insulin resistance
  • type diabetes
  • healthcare
  • high fat diet induced
  • palliative care
  • genome wide
  • dna methylation
  • adipose tissue
  • skeletal muscle
  • smoking cessation