Lack of association between CYP27B1 gene polymorphism and type 2 diabetes mellitus in Iranian patients.

Published in: Journal of diabetes and metabolic disorders (2022)

We found no association between rs10877012 polymorphism and T2DM. There was no increased risk of this polymorphism in T2DM. Further studies with large groups are suggested in other populations to better understand the relation of CYP27B1 gene variation, especially its ethnicity-dependent relation with T2DM.

Keyphrases

glycemic control
end stage renal disease
ejection fraction
newly diagnosed
prognostic factors
peritoneal dialysis
gene expression
cardiovascular disease
metabolic syndrome
skeletal muscle
weight loss