Tumor budding and adjacent tissue at the invasive front correlate with delayed neck metastasis in clinical early-stage tongue squamous cell carcinoma.
Nobuhiro YamakawaTadaaki KiritaMasahiro UmedaSouichi YanamotoYoshihide OtaMitsunobu OtsuruMasaya OkuraHiroshi KuritaShin-Ichi YamadaTakumi HasegawaTomonao AikawaTakahide KomoriMichihiro Uedanull nullPublished in: Journal of surgical oncology (2018)
In addition to conventional predictors, high grade tumor budding and adjacent tissue at the invasive front can serve as useful predictors of DNM in early tongue cancer.