Efficacy and Safety of AbobotulinumtoxinA for the Treatment of Hemiparesis in Adults with Lower Limb Spasticity Previously Treated With Other Botulinum Toxins: A Secondary Analysis of a Randomized Controlled Trial.
Alberto EsquenaziGaëtan StoquartPeter HederaLuis Jorge JacintoUgo DimanicoFrancois Constant-BoyerAllison BrashearAnne-Sophie GrandoulierClaire VilainPhilippe PicautJean-Michel GraciesPublished in: PM & R : the journal of injury, function, and rehabilitation (2020)
Patients previously treated with other BoNT-As showed improved muscle tone and spasticity at week 4 following abobotulinumtoxinA injection versus placebo. These findings suggest that abobotulinumtoxinA, at the recommended doses, has a good safety and efficacy profile in adults with lower limb spasticity who were previously treated with other BoNT-A products.