Heart rate variability associated with acute exercise challenge in children with sickle cell anaemia.
Stephan L KienzleMark RodeghierRobert I LiemPublished in: British journal of haematology (2021)
We examined heart rate variability (HRV) during exercise testing in 20 children with sickle cell anaemia (SCA) and 12 controls. Subjects achieved lower median HRV at peak exercise [standard deviation of R-wave to R-wave intervals (SDNN), 2·3 vs 2·9 ms, P = 0·027; logarithmic transformation of high frequency power (lnHF), 0·9 vs 1·3 ln(ms2 ), P = 0·047] and had lower post-exercise HRV across minute-by-minute analysis of recovery. After adjustment for haemoglobin, fitness and SCA status, subjects had lower HRV at the end of recovery with differences increasing as baseline HRV increased. Further investigation of HRV and exercise safety in SCA is warranted.
Keyphrases
- heart rate variability
- high intensity
- physical activity
- high frequency
- heart rate
- resistance training
- multiple sclerosis
- mass spectrometry
- young adults
- transcranial magnetic stimulation
- ms ms
- body composition
- blood pressure
- liver failure
- intensive care unit
- acute respiratory distress syndrome
- iron deficiency
- aortic dissection