Cardiovascular health and four epigenetic clocks.

Published in: Clinical epigenetics (2022)

This is one of the first studies to comprehensively investigate the associations of CVH with four epigenetic clocks. Our TWB data showed that ideal CVH is associated with lower levels of EAA calculated according to the second-generation epigenetic clocks (PhenoEAA and GrimEAA). Having an ideal CVH status can lower EAA and reduce the risk of aging-related disorders.

Keyphrases

dna methylation
gene expression
electronic health record
big data
machine learning
case control