Elevated Platelet Count Appears to Be Causally Associated with Increased Risk of Lung Cancer: A Mendelian Randomization Analysis.
Ying ZhuYongyue WeiRuyang ZhangXuesi DongSipeng ShenYang ZhaoJianling BaiDemetrius AlbanesNeil E CaporasoMaria Teresa LandiBin ZhuStephen J ChanockFangyi GuStephen LamMing-Sound TsaoFrances A ShepherdAdonina TardónAna Fernandez-SomoanoGuillermo Fernandez-TardónChu ChenMatthew J BarnettJennifer DohertyStig E BojesenMattias JohanssonPaul BrennanJames D McKayRobert Carreras-TorresThomas MuleyAngela RischHeunz-Erich WichmannHeike BickeboellerAlbert RosenbergerGadi RennertWalid SalibaSusanne M ArnoldJohn K FieldMichael P A DaviesMichael W MarcusXifeng WuYuanqing YeLoic Le MarchandLynne R WilkensOlle MelanderJonas ManjerHans BrunnströmRayjean J HungGeoffrey LiuYonathan BrhaneLinda KachuriAngeline S AndrewEric Jeffrey DuellLambertus A L M KiemeneyErik H F M van der HeijdenAage HaugenShanbeh ZienolddinyVidar SkaugKjell GrankvistMikael JohanssonPenella J WollAngela CoxFiona TaylorDawn M TearePhilip LazarusMatthew B SchabathMelinda C AldrichRichard S HoulstonJohn McLaughlinVictoria L StevensHongbing ShenZhibin HuJuncheng DaiChristopher Ian AmosYounghun HanDakai ZhuGary E GoodmanFeng ChenDavid Chistopher ChristianiPublished in: Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology (2019)
These findings provide a better understanding of lung cancer etiology and potential evidence for antiplatelet interventions for lung cancer prevention.