From an assessment of multiple chelators, clodronate has potential for use in continuous chelation.
Patricia Paule WrightC CooperBill KahlerJames Laurence WalshPublished in: International endodontic journal (2019)
Alkaline 0.5 mol L-1 clodronate mixed equally with 10% NaOCl has potential for use in continuous chelation, based on this assessment of stability and smear layer removal. Further research is needed to establish its efficacy and safety.