Plant-Derived Natural Products as Lead Agents against Common Respiratory Diseases.
Ayodeji Oluwabunmi OriolaAdebola Omowunmi OyedejiPublished in: Molecules (Basel, Switzerland) (2022)
Never has the world been more challenged by respiratory diseases (RDs) than it has witnessed in the last few decades. This is evident in the plethora of acute and chronic respiratory conditions, ranging from asthma and chronic obstructive pulmonary disease (COPD) to multidrug-resistant tuberculosis, pneumonia, influenza, and more recently, the novel coronavirus (COVID-19) disease. Unfortunately, the emergence of drug-resistant strains of pathogens, drug toxicity and side effects are drawbacks to effective chemotherapeutic management of RDs; hence, our focus on natural sources because of their unique chemical diversities and novel therapeutic applications. This review provides a summary on some common RDs, their management strategies, and the prospect of plant-derived natural products in the search for new drugs against common respiratory diseases.
Keyphrases
- drug resistant
- multidrug resistant
- chronic obstructive pulmonary disease
- gram negative
- acinetobacter baumannii
- lung function
- sars cov
- respiratory tract
- drug induced
- mycobacterium tuberculosis
- liver failure
- respiratory failure
- escherichia coli
- oxidative stress
- cystic fibrosis
- hepatitis b virus
- extracorporeal membrane oxygenation
- pulmonary tuberculosis
- air pollution
- respiratory syndrome coronavirus
- oxide nanoparticles