A Triple Combination of Metformin, Acetylsalicylic Acid, and Oseltamivir Phosphate Impacts Tumour Spheroid Viability and Upends Chemoresistance in Triple-Negative Breast Cancer.
Manpreet SambiVanessa SamuelBessi QorriSabah HaqSergey V BurovElena MarkvichevaWilliam HarlessMyron R SzewczukPublished in: Drug design, development and therapy (2020)
For the first time, the findings demonstrate that repurposing ASA, Met, and OP provides a novel and promising targeted multimodal approach in the treatment of triple-negative breast cancer and its chemoresistant variant.