Interconnectivity between molecular subtypes and tumor stage in colorectal cancer.
R R J Coebergh van den BraakS Ten HoornA M SieuwertsJ B TuynmanM SmidS M WiltingJ W M MartensC J A PuntJ A FoekensJ P MedemaJ N M IJzermansLouis VermeulenPublished in: BMC cancer (2020)
Considerable interconnectivity between tumor biology and tumor stage in CRC exists. This implies that the TNM stage, in addition to the stage of progression, might also reflect distinct biological disease entities. These insights can potentially be utilized to optimize identification of high-risk stage II colon cancers.
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