Gene expression within the periaqueductal gray is linked to vocal behavior and early-onset parkinsonism in Pink1 knockout rats.

Published in: BMC genomics (2020)

Overall, this work supports the premise that gene expression changes in the PAG may contribute to the vocal deficits observed in this PD rat model. Additionally, this dataset identifies genes that represent new therapeutic targets for PD voice disorders.

Keyphrases

gene expression
early onset
genome wide
dna methylation
late onset
traumatic brain injury
parkinson disease
drug induced
wild type