Case-control study of adverse childhood experiences and multiple sclerosis risk and clinical outcomes.

Mary K HortonShannon McCurdyXiaorong ShaoKalliope BellesisTerrence ChinnCatherine SchaeferLisa F Barcellos

Published in: PloS one (2022)

Despite rich data and multiple approaches to operationalizing ACEs, no consistent and statistically significant effects were observed between ACEs with MS. This highlights the challenges of studying sensitive, retrospective events among adults that occurred decades before data collection.

Keyphrases

multiple sclerosis
electronic health record
big data
mass spectrometry
mental health
emergency department
adverse drug
deep learning