Genetic Polymorphisms in ERCC1 Gene and Their Association with Response to Radiotherapy in Moroccan Patients with Nasopharyngeal Carcinoma.

Rajaa Benzeid Amina GihbidNezha TawfiqNadia BenchakrounKarima BendahhouAbdelatif BeniderAmal GuensiNaima El BennaAbdelkarim Filali MaltoufMohammed AttalebImane ChaouiMeriem Khyatti Mohammed Elmzibri

Published in: Asian Pacific journal of cancer prevention : APJCP (2023)

Our results clearly showed that ERCC1 C8092A and ERCC1 C118T polymorphisms were not associated with response to radiotherapy in Moroccan NPC patients. Large studies are warranted to confirm the role of these SNPs in therapeutic response of NPC patients.

Keyphrases

end stage renal disease
newly diagnosed
ejection fraction
dna repair
genome wide
squamous cell carcinoma
locally advanced
radiation induced
patient reported outcomes
dna damage