First Report of OXA-181-Producing Klebsiella pneumoniae in China.

Congcong LiuYinfei FangYu ZengJiayue LuQiaoling Sun Hongwei ZhouZhangqi ShenGongxiang Chen

Published in: Infection and drug resistance (2020)

We present here the first report of an OXA-181-producing Klebsiella pneumoniae isolated from the fecal specimen of a patient in China. The OXA-181-encoding gene bla OXA-181 was located on a 51 kb IncX3-type plasmid. Conjugation assay and whole-genome sequencing analysis revealed that this transferrable plasmid in the K. pneumoniae isolate might have originated from Escherichia coli and have the potential to mediate the spread of bla OXA-181.

Keyphrases

klebsiella pneumoniae
escherichia coli
multidrug resistant
acinetobacter baumannii
crispr cas
high throughput
drug resistant
case report
gene expression
copy number
single cell
candida albicans
genome wide identification