Analysis of NSCLC tumour heterogeneity, proliferative and 18F-FDG PET indices reveals Ki67 prognostic role in adenocarcinomas.
Alessandro Del GobboAlessio PellegrinelliGabriella GaudiosoMassimo CastellaniFederica Zito MarinoRenato FrancoAlessandro PalleschiMario NosottiSilvano BosariValentina VairaStefano FerreroPublished in: Histopathology (2015)
Our results highlight how tumour heterogeneity influences evaluation of prognostic biomarkers. Our data support Ki67 evaluation to estimate NSCLC patients' prognosis, particularly for adenocarcinoma.
Keyphrases
- small cell lung cancer
- end stage renal disease
- pet ct
- positron emission tomography
- newly diagnosed
- single cell
- ejection fraction
- chronic kidney disease
- advanced non small cell lung cancer
- squamous cell carcinoma
- pet imaging
- computed tomography
- neoadjuvant chemotherapy
- peritoneal dialysis
- electronic health record
- big data
- radiation therapy
- brain metastases
- locally advanced
- rectal cancer
- data analysis