Voltammetric Determination of Favipiravir Used as an Antiviral Drug for the Treatment of Covid-19 at Pencil Graphite Electrode.
Teslime ErşanDidem Giray DilginElif KumruluUmur KumruluYusuf DilginPublished in: Electroanalysis (2022)
This work describes the sensitive voltammetric determination of favipiravir (FAV) based on its reduction for the first time with a low-cost and disposable pencil graphite electrode (PGE). In addition, the determination of FAV was also performed based on its oxidation. Differential pulse (DP) voltammograms recorded in 0.5 M H 2 SO 4 for the reduction of FAV show that peak currents increase linearly in the range of 1.0 to 600.0 μM with a limit of detection of 0.35 μM. The acceptable recovery values (98.9-106.0 %) obtained from a pharmaceutical tablet, real human urine, and artificial blood serum samples spiked with FAV confirm the high accuracy of the proposed method.
Keyphrases
- molecularly imprinted
- low cost
- solid phase extraction
- coronavirus disease
- endothelial cells
- sars cov
- blood pressure
- carbon nanotubes
- induced pluripotent stem cells
- mass spectrometry
- nitric oxide
- label free
- real time pcr
- loop mediated isothermal amplification
- sensitive detection
- respiratory syndrome coronavirus
- smoking cessation
- liquid chromatography