Antihypertensive Effect Of Amlodipine In Co-Administration With Omeprazole In Patients With Hypertension And Acid-Related Disorders: Cytochrome P450-Associated Aspects.

Margarita N DorofeevaEvgenia V ShikhZhanna M SizovaAlisa V TarasenkoNatalia P DenisenkoValeriy V SmirnovKristina Anatolyevna AkmalovaZhannet A SozaevaElena A GrishinaDmitriy A Sychev

Published in: Pharmacogenomics and personalized medicine (2019)

Adding omeprazole to long-term amlodipine therapy in patients with hypertension and ARD may lead to a significantly more pronounced antihypertensive effect in patients genotyped CYP2C19 IMs.

Keyphrases

blood pressure
hypertensive patients
end stage renal disease
ejection fraction
chronic kidney disease
newly diagnosed
peritoneal dialysis
prognostic factors
patient reported outcomes
mesenchymal stem cells
smoking cessation
cell therapy