RH genotyping by nonspecific quantitative next-generation sequencing.
Marianne StefKatie FennellIzaskun ApraizDavid ArtetaCecilia González-SantestebanNuria NoguésGorka Ochoa-GarayPublished in: Transfusion (2020)
Nonspecific sequencing of homologous gene sets combines detection and quantification of genetic variation in a single assay. Evidence is provided for the quantitative nature of the method, its sensitivity and specificity, and its ability to identify complex RH genotypes.