Effects of APOE haplotypes and measures of cardiovascular risk over gender-dependent cognitive and functional changes in one year in Alzheimer's disease.

Fabricio Ferreira de Oliveira Fernando Vieira Pereira Glaucia Akiko Kamikado Pivi Marilia de Arruda Cardoso Smith Paulo Henrique Ferreira Bertolucci

Published in: The International journal of neuroscience (2017)

Higher BMI and creatinine clearance are protective regarding cognitive and functional decline for women, whereas higher cognitive reserve may lead to faster decline in instrumental functionality. APOE haplotypes affected the age at AD onset, but not cognitive or functional decline.

Keyphrases

cognitive decline
high fat diet
pregnant women
polycystic ovary syndrome
metabolic syndrome
weight gain
uric acid
pregnancy outcomes