Tumor microenvironment reprogramming improves nanomedicine-based chemo-immunotherapy in sarcomas.

Antonia Charalambous Fotios Mpekris Myrofora Panagi Chrysovalantis Voutouri Christina Michael Alberto A Gabizon Triantafyllos Stylianopoulos

Published in: Molecular cancer therapeutics (2024)

Collectively, our findings provide evidence that ketotifen-induced TME reprograming can improve the efficacy of nanomedicine-based chemoimmunotherapy in sarcomas.

Keyphrases

cancer therapy
high grade
high glucose
diabetic rats
photodynamic therapy
drug delivery
drug induced
oxidative stress
combination therapy
endothelial cells
rectal cancer