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Impaired Behavioral Pattern Separation in Refractory Temporal Lobe Epilepsy and Mild Cognitive Impairment.

Sanam J LalaniAnny ReyesErik KaestnerShauna M StarkCraig E L StarkDavid LeeLeena KansalJerry J ShihChristine N SmithBrianna M PaulCarrie R McDonald
Published in: Journal of the International Neuropsychological Society : JINS (2021)
Memory performance on a task that relies on PS was disrupted to a similar extent in TLE and aMCI. The MST could provide a clinically useful tool for measuring hippocampus-dependent memory impairments in TLE and other neurological disorders associated with hippocampal damage.
Keyphrases
  • mild cognitive impairment
  • temporal lobe epilepsy
  • cognitive decline
  • working memory
  • cerebral ischemia
  • oxidative stress
  • resting state
  • subarachnoid hemorrhage
  • brain injury
  • prefrontal cortex
  • functional connectivity