NKT-dependent B-cell activation in Gaucher disease.

Published in: Blood (2015)

In this issue of Blood, Nair et al describe a new population of type II natural killer T (NKT) cells with follicular helper phenotype (TFH), which is more abundant in patients and mice with Gaucher disease (GD) and is capable of regulating B-cell activity.

Keyphrases

end stage renal disease
newly diagnosed
ejection fraction
induced apoptosis
replacement therapy
chronic kidney disease
prognostic factors
peritoneal dialysis
cell cycle arrest
dendritic cells
type diabetes
adipose tissue
metabolic syndrome
skeletal muscle
cell proliferation
signaling pathway
nk cells