Outcomes of early versus delayed weight-bearing with intramedullary nailing of tibial shaft fractures: a systematic review and meta-analysis.

Ameya Bhanushali Joshua G Kovoor Brandon Stretton James T Kieu Rebecca A Bright Joseph N Hewitt Christopher D Ovenden Aashray K Gupta Mohamed Zaafer Afzal Suzanne Melissa Edwards Ruurd L Jaarsma Christy Graff

Published in: European journal of trauma and emergency surgery : official publication of the European Trauma Society (2022)

The included studies were of moderate risk of bias and demonstrated shorter union time and fewer complications with EWB. However, current evidence is minimal and has significant limitations. The role of EWB in high-risk patients is yet to be examined. Further well-designed, randomised studies are required on the topic.

Keyphrases

end stage renal disease
clinical trial
ejection fraction
newly diagnosed
case control
body mass index
total knee arthroplasty
physical activity
open label
prognostic factors
risk factors
weight loss
type diabetes
study protocol
high intensity
patient reported outcomes