Genetic Evidence Causally Linking Pancreas Fat to Pancreatic Cancer: A Mendelian Randomization Study.

Hajime YamazakiSamantha A StreicherLang WuShunichi FukuharaRóbert WagnerMartin HeniSteven R GrossmanHeinz-Josef LenzVeronica Wendy SetiawanLoic Le MarchandBrian Z Huang

Published in: medRxiv : the preprint server for health sciences (2023)

This study provides genetic evidence for a causal role of pancreas fat in the pathogenesis of PDAC. Thus, reducing pancreas fat could lower the risk of PDAC.

Keyphrases

adipose tissue
genome wide
copy number