Berberine promotes immunological outcomes and decreases neuroinflammation in the experimental model of multiple sclerosis through the expansion of Treg and Th2 cells.

Maryam J TavafAzita SoltanmohammadiSimin ZargaraniEsmaeil YazdanpanahBizhan SadighimoghaddamBahman YousefiHamid R SameniDariush Haghmorad

Published in: Immunity, inflammation and disease (2023)

Berberine appears to have a protective effect on disease development and alleviating disease status in EAE, which appears to be due to the cell expansion and function of Treg and Th2 cells in addition to berberine's anti-inflammatory properties.

Keyphrases

induced apoptosis
multiple sclerosis
cell cycle arrest
anti inflammatory
endoplasmic reticulum stress
traumatic brain injury
single cell
cell death
lipopolysaccharide induced
mesenchymal stem cells
adipose tissue
cell proliferation
white matter
cognitive impairment
subarachnoid hemorrhage