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GGT1 Suppresses the Development of Ferroptosis and Autophagy in Mouse Retinal Ganglion Cell Through Targeting GCLC.

Guihua XuJuanjuan WangYiting ZhangZilin ChenRuidong Deng
Published in: Eye and brain (2023)
GGT1 represses autophagy in RGC-5 cells by targeting GCLC, which further restrains the development of ferroptosis in cells.
Keyphrases
  • cell death
  • cell cycle arrest
  • induced apoptosis
  • signaling pathway
  • endoplasmic reticulum stress
  • oxidative stress
  • single cell
  • cell therapy
  • stem cells
  • cancer therapy
  • mesenchymal stem cells
  • bone marrow